Project: One step in a mile: revisiting insulitis in Type 1 Diabetes
Supervisor:
Project: Translational Test Models for Functional Assessment of Bioactive Wound Dressings in Chronic Wound Environments
Supervisor:
Project: Evaluating the role of succinate sending via GPR91 in T cell-mediated anti-tumour immunity
Supervisor:
Project: Development of Next-Generation Potassium Ion Biosensors
Supervisor:
Project: Trophoblastic anticoagulant proteins at the implantation front
Supervisor:
Project: Genetic events in teh progression from precancerous lesions in inavive carcinoma
Supervisor:
Project: Live-cell fluorescence imaging of cell signaling and metabolism on cell-Mg-implant interfaces and in cancer cells
Supervisor:
Project: Environmental enrichment modulates behaviour via microbiota-gut-brain axis signalling
Supervisor:
Project: Bioinformatic characterization of the molecular background affecting treatment response in early-stage and metastatic cancer
Supervisor:
Project: Targeting mitochobndria-autophagy circuits in heart failure with preserved ejection fraction
Supervisor:
Project: The impact of mitochondrial-ER interplay on metabolism during aging
Supervisor:
Project: Effects of altered microbiota-gut-brain axis siganlling on aggressive behavior
Supervisor:
Project: Temporal filtering in motion vision
Supervisor:
Project: The molecular circadian clock in pulmonary fibrosis and chronic obstructive pulmonary disease
Supervisor:
Grebe Alexandra
Project: Characterization of PNPLA3 enzyme function via small-molecule inhibitors
Supervisor:
Project: explore the diversity and function f the excreted and exposed proteins of human-associated archaeaand their roles in biofilm formation
Supervisor:
Project: CXCR4 role in the anabolic responses of teriparadide in bone
Supervisor:
Project: Modeling reproductive failure in humans
Supervisor:
Project: Biomarker and resitance mechanisms of hormone receptor-positive breast cancer
Supervisor:
Project: The role of LYVE-1 Hofbauer cells in preeclampsia
Supervisor:
Project: Interplay of gluconeogenesis and gycolysis in lung cancer
Supervisor:
Project: Drug-microbiome interaction in liver cirrhosis
Supervisor:
Project: Identification and characterization of novel gene candidates regulating aggression
Supervisor:
Project: MIDAS - inflammatory mechanisms involved in Diabetes uncovered by tissue imaging and machine learning
Supervisor:
Project: Deciphering the role of lipolysis in brain and energy metabolism
Supervisor:
Project: Metabolism and fucntion of naive DC4+ T cells in primary Sj枚gren's syndrome
Supervisor:
Project: Metabolic adaption of cancer cells to glucose deprivation
Supervisor:
Project: Therapeutic potentila of antimicrobial peptides in atopic dermatitis
Supervisor:
Project: CDK9 inhibition in RAS-mutated chronic myelomonocytic leukemia (CMML)
Supervisor:
Project: Investigating the influence of Mg-deficiency on callus quality and fracture healing in high-fat undiced obese mice after transplantation of metallic material
Supervisor:
Project: Elucidating the pathogenic role of acyl-coenzyme A binding protein (ACBP) in age-related cardiac decline
Supervisor:
Project: Identification of antigen-specific T cells via Ca2+ - NFAT signaling in non-small cell lung cancer
Supervisor:
Project: CaMKII-mediated (inflammatory) signaling in hypertensive heart disease
Supervisor:
Project:
Supervisor:
Project: The initiation and evolution of rare cancers
Supervisor:
Project: The crosstalk between gut hormones and endothelial cells in cardiometabolic disease
Supervisor:
Project: Correlation of tumor size and biology with the release of ct-DNA in early colorectal cancer
Supervisor:
Project: Neprilysin in pregnancy
Supervisor:
Project: Maternal obesity and its impact on the placental extracellular matrix composition
Supervisor:
Project: Liquid biopsies for eraly detection of cancer
Supervisor:
Project: Atypical chemokine receptors in kidney disease
Project: Probing cellular aging with fluorescent receptors
Supervisor:
Project: Neutrophil elastase and myeloperoxidase in the tumor microenvironment of NSCLC
Supervisor:
Project: Succinate in human placental vasculature in GDM
Supervisor:
Project: Discovery of positive allosteric modulators for the treatment of mannosidosis
Supervisor:
Magaard-Romano Carlo
Project: Principles of archaeal-bacterial interaction in host systems
Supervisor:
Project: The role of extracellular vesicles as emrging modulators of anticancer drug resistance
Supervisor:
Project: Metabolic regulation of Th9 cells
Supervisor:
Project: Temporal dynamics of blood biomarkers in relation to clinical and radiologicla disease worsening in multiple sklerosis
Supervisor:
Project: Replace Mice Xenografts by Microfluidic CancerogEnesis Chips 鈥� ReplaceMICE
Supervisor:
Project: Enhanced protein synthesis by synchronous yeast cells
Supervisor:
Project: Transcriptional Reprogramming of the Hypertensive Heart
Supervisor:
Mayer Marie-Christin
Project: Small RAS-mutated clones and the bone marrow microenvironment in myeloid neoplasms
Supervisor:
Project: Investigating the influence of Mg-based implants on chondrocytes
Supervisor:
Project:
Supervisor:
Project: PANcreatic CAncer Initial Dectection via liquid biopsy (PANCAID)
Supervisor:
Project: Exploring the Immunomodulatory Role of Archaeal Extracellular Vesicles in Macrophage Function and Host Immunity
Supervisor:
Project: LAMB3-DAG1 axis in early placental developement
Supervisor:
Project: Mitochondrial Dysfunction in Aging and Dravet Syndrome 鈥� Mechanisms and Targeting
Supervisor:
Project: Role of macrophage LAL in the small intestine and contribution of neutral and acidic lipolysis to fatty acid release
Supervisor:
Project: Trophoblastic anticoagulant proteins at the implantation front
Supervisor:
Project: Bile acid-mediated tissue factor activation in hepatocytes
Supervisor:
Project: Novel biomarker and statistical approaches for prediction of recurrent cardiovascular events
Supervisor:
Project: Prone adiposity: programming of neonatal adipose by maternal gestational diabetes
Supervisor:
Project: Designing the niche space of the human gut microbiome
Supervisor:
Project: Identifying the hematopoietic and leukemic stem cell niches
Supervisor:
Project: T3-induced rewiring of mitochondrail Ca2+ in cancer cells
Supervisor:
Project: Cardiovascular risk prediction using multiparametric analysis of the human serum proteome
Supervisor:
Project: Environmental modulation of microbiota-gut-brain axis signalling during experimental colitis
Supervsior:
Project: Novel metabolic biomarkers of aging and age-related diseases
Supervisor:
Petrucci Lorenzo
Project: Monitoring and interfering with glioblastoma network formation with bioelectronic technologies
Supervisor:
Project: Impact of inflammation on disease progression and extracellular matrix remodeling in failing hearts
Supervisor:
Project: Computer-aided (re)design of enzymes for therapeutics
Supervisor:
Project: Dissecting Cytokine Signaling for Precision Targeting of Therapy-Resistant Leukemic Stem Cells in AML
Supervisor:
Project: Effect of EL modified HDL on cholesterol and oxysterol induced endothelila dysfunction
Supervisor:
Project: BAMBinO: bile acids as metabolic regulators in osteoporosis
Supervisor:
Project: Interorgan communication and NAD+ metabolism in exercise and cardiometabolic disease
Supervisor:
Project:
Supervisor:
Project: LAM dynamics during weight cycling
Supervisor:
Project: Immune heterogeneity of the tumor microenvironment and the endocannabinoid system
Supervisor:
Project: Circulating tumor DNA for detection of localized prostate cancer
Supervisor:
Project: Molecular insights into Ca2+ supply of the endoplasmic reticulum
Supervisor:
Project: Vascular health and maternal adaptation in cardiometabolic complications of pregnancy
Supervisor:
Project: precision medicine for people with muco-obstructive lung disease
Supervisor:
Project: Harnessing Immunogenic Cell Death for Improved Lung Cancer Therapy
Supervisor:
Project: The clinical relevance of the NR4A1/p53 axis in diffuse large B cell lymphoma
Supervisor:
Project: Antihypertensive mechanism of spermidine
Supervisor:
Project: Elucidating the key mechanistic steps of reticulocyte to erythrocyte transition in vivo and ex vivo using light sheet ultramicroscopy and scRNAseq analyses
Supervisor:
Project: Identification of tumor-specific metabolite antigens
Supervisor:
Project: Characetrization of two new possible trigyceride hydrolases
Supervisor:
Project: Microchimeric cells: distribution of microchimeric cells in offspring of genetically identical and non-identical parents (mouse model)
Supervisor:
Project: The Contribution of Lipids to Intrahepatic Coagulation During Cholestatic Liver Injury
Supervisor:
Project: Targeting cancer cell mitochondria to increase their vulnerability to cytotoxic T-cell killing
Supervisor:
Project: The microbiome of the small intestine
Supervisor:
Project: The immunomodulatory effects of the NR4A1/p53 axis in diffuse large B cell lymphoma
Supervisor:
Project: Microchimeric cells: trans-placental route to and presence in the host
Supervisor:
Project: Impact of inflammation on atherosclerosis pregression post MI
Supervisor:
Project: Deciphering the intricate role of FOXO proteins in health and disease
Supervisor:
Project: Impact of maternal obesity on immune function of fetal endothelial cells
Supervisor:
Project: Effect of pharmacological inhibition of ATGL-mediated lipolysis in WAT by Atglistatin on cardiometabolic health and the HFpEF phenotype
Supervisor:
Suresh Krishna
Project: Archaeome-immune system interactions
Supervisor:
Project: Investigating the function of nNR4A nuclear receptor family in Myc-driven lyphomagenesis
Supervisor:
Project: The role of neuronal and glial biomarkers to indicate disease worsening in multiple sclerosis
Supervisor:
Project: Invasive properties of trophoblast subtypes during implantation and early placentation
Supervisor:
Project: Targeted drug delivery by an ionotropic implant for tunable chemoimmunotherapy
Supervisor:
Project: Ionotropic chemoimmunotherapy for the treatment of local and distal in vivo tumors
Supervisor:
Project: Design and biophysical characterization of peptidomimetics as CRAC channel modulators
Supervisor:
Project: Exploring the crosstalk between immune and non-immune cells in the rheumatoid arthritis synovium
Supervisor:
Project: Development and cellular characterization of next-generation biosensors
Supervisor:
Project:
Supervisor:
Project: Targeting growth factor signaling to promote cardiovascular health in aging
Supervisor:
Project: Cardioprotective effects of combined exercise and NAD+ replenishment in rats with cardiometabolic syndrome
Supervisor:
Project: Alterations in DNA repair genes are associated with platinum sensitivity in metastatic prostate patients
Supervisor:
Project: A potential novel liver-adipose axis activated by FXR to induce browning and thermogenesis in obese patients with MASLD
Supervisor:
Project:
Supervisor:
Project: Neural circuits for path integration
Supervisor:
Project: Skewed chromosome X inactivation as a driver of pro.-inflammatory and metabolic disturbances in pulmonary vascular disease
Supervisor:
Weber Laurenz
Project: Decoding and Targeting Mitochondria鈥揈R Crosstalk in Cellular and Organismal Aging
Supervisor:
Project: Metabotyping nutrient deprivation response in cancer therapy
Supervisor:
Project: P53 regulation of lipid-associated macrophages upon fasting in liver disease
Supervisor:
Project: Archaea interactions in mammal gut microbiota
Supervisor:
Project: Endoplasmic reticulum stress and mitochondrial dysfunction in airway diseases
Supervisor:
Project: Controlled degradation of nanorobots via computationally-engineered biocatalysts
Supervisor:
Project: Peptide YY in colitis and gut-brain siganling
Supervisor:
Project: Pioneering inflammation resolution with engineered high-density lipoproteins
Supervisor:
Project: An epigenetic-metabolic crosstalk reveals vulnerabilities of acquired drug resistance
Supervisor:
Project: NR4A-1 mediated regulation of immune evation in lymphoma
Gampawar Piyush Gajananrao: Genetic determinants of brain ageing Supervisor: Helena Schmidt
Forstner Desiree: Effects of maternal platelets on trophoblasts Supervisor: Martin Gauster
Birkl-T枚glhofer Anna Maria: Drug-induced liver injury in psychiatric disorders Supervisor: Johannes Haybck
Hinteregger Barbara: Integration of metabolomics and already established approaches for characetrization of an Alzheimer's Disease Model Supervisor: Tobias Madl
Ramadani-Muja Jeta: Development and application of fluorescent protein-based probes to determine protein targeting mitochondria Supervisor: Roland Malli
Zhou Qin: Tumor Genome Stratification and Network Analyses based on Non-invasive Liquid Biopsies Supervisor: Michael Speicher
Burgstaller, Sandra: Visualization of local intracellular & cell surface cation alterations using fluorescent protein-based probes Supervisor: Roland Malli
Del Gaudio, Ilaria:The role of (S1P)-HDL on endothelial barrier function by gestational diabetes mellitus Supervisor: Christian Wadsack
Pausan, Manuela-Racula: Interacting microbes - the microcosmos in our body and our homes Supervisor: Christine Moissl-Eichinger
Alumni 2019
K茅tszeri M谩t茅 Csaba: The role of microRNA-142-3p in uremic vascular media calcification Supervisor: Alexander Rosenkranz
Francic, Vito: Vitamin D, clinical outcome and regulation of metabolism Barbara Obermayer-Pietsch
Matak Andrija: Characterization of cancer specific mechanisms in hepatobiliary carcinoma Supervisor: Kurt Zatloukal
Caraffini, Veronica: Analysis of the role of RAF kminase inhibitor protein innthe development of myeloid neoplasias Supervisor: Armin Zebisch
Abdellatif, Mahmoud: Cardioprotective mechanisms of spermidine in aging and related cardiovascular disease Supervisor: Simon Sedej
Daga, Shruti: Leukemic stem cells and a novel method of minimal residual disease detection in acute myeloid leukemia Supervisor: Albert W枚lfler
Gungl, Anna: Inflammatory profiling reveals Type 2 predominant eosinophilic inflammation and asthmatic airway disease in the Fra2 transgenic mouse model Supervisor: Grazyna Kwapiszewska
Mora, Maximiliam: Microbes in restricted indoor environments - with focus on International Space Station and spacecraft associated celan rooms Supervisor: Christine Moissl-Eichinger
Bischof, Helmut: Development, characterization and application of novel genetically encoded, fluorescent potassium ion indicators Supervisor: Roland Malli
Stryeck, Sarah: Deciphering the intricate interaction network in the beta-catenin destruction complex - the Axin-1 paradigm Supervisor: Tobias Madl
Fechter, Karoline: Investigating the role of NR4A1 in aggressive lymphomas Supervisor: Andreas Prokesch & Alexander Deutsch
Unterluggauer, julia Judith: Investigating the role of translation initiation factors in aggressive B-cell lymphoma Supervisor: Johannes Haybck
L枚gl, Jelena: Paracrine regulation of feto-placental angiogenesis by placental macrophages and trophoblasts Supervisor: Gernot Desoye
